Mikhail Blagosklonny Works to Fight Cancer . . . and Aging.

Rapamycin is a compound that is used to prevent organ transplant rejection and to coat coronary stents. But according to Dr. Mikhail Blagosklonny, it can serve other purposes. The professor of oncology at Roswell Park Cancer Institute has come up with a hypothesis that rapamycin can be used not only to treat cancer, but to help slow the aging process.

Blagosklonny believes that TOR Signaling, which utilizes rapamycin, can be used in both treatments. The mTOR pathway helps regulate metabolism and physiology. Much of Blagosklonny’s research involves molecular and cellular biology as it relates to protecting healthy cells from damage by cancer, and slowing the aging process and halting age related diseases.

Along with his research work, Mikhail Blagosklonny published numerous papers in peer reviewed journals going back to 2000. Topics he has written about include TOR signaling, selective cancer therapy, and diabetic complications. He is also the editor-in-chief of three different medical related periodicals. They are Aging, Cell Cycle, and Oncotarget. View Mikhail’s profile on Loop

Blagosklonny came to the Roswell Park Cancer Institute in Buffalo, New York in 2009. His main job is to develop various anti-cancer strategies. Some of those strategies involve trying to prevent cancer by slowing the aging process.

Dr. Mikhail Blagosklonny received his PhD from First Pavlov State Medical University of St. Petersburg in Russia. Coming to the United States, he worked as a professor of medicine at New York Medical Center and a senior scientist at Albany’s Ordway Research Institute before going on to Roswell Park. Read more  https://scholar.google.com/citations?user=REO9YogAAAAJ&hl=en

Even Warren Buffett Can Be Wrong About Investment

Warren Buffett talks about the mediocre funds that are expensive and shortchange the investors. Tim Armour agrees with this view and supports simple investments that are low in cost. He says that these are long terms investments that should be bought and just held. The investment strategy of Warren Buffett does not need any proof of approval. Hence he is the best person to say that Americans have to save more in order to cater for their retirement needs. They must invest and stay invested.

The consumers need to look at the product closely. There are a number of mutual funds that are providing mediocre or really poor returns in the long-run. This can be due to the high management fees associated with them or due to excessive trading. Besides, consumers are not aware of volatility risks. Even the opportunity costs of all these passive investments may be typically unknown. Hence the issue here is not about being active or passive. Rather it is all about the long-term basis of investment returns. A key component of these returns will be low costs.

Read more on Bloomberg.

Hence passive index returns cannot be considered as safe for retirement any more. Index funds do have an important place, but they cannot be a cushion against the markets being down. The main issue here is that people are now aware of the volatility as well as losses in case of market downturns.

Another fact is that the actively managed funds have not done that well in terms of the market over a meaningful time frame. Tim does talk about exceptions, though.

Tim Armour is the Chairman of Capital Group, and its Chief Executive Officer too. He stated that Warren Buffett is putting on $1 million for charity. But he would have done better by simply investing it in the S&P 500 passive index fund.

Learn more about Tim Armour: https://www.thecapitalgroup.com/us/about.html

Creative Businessman Alexandre Gama Continues to Wow the World with His Work

Brazilian businessman, Alexandre Gama, has established himself as one of the leading creative entrepreneurs in Brazil, as well as a globally hailed thought leader in the advertising industry. Neogama, the advertising agency that Alexandre founded nearly two decades ago, continues to garner awards and praise for the thought provoking and internationally acclaimed work that the agency continuously produces.

Presently, Alexandre Gama serves as a member of the Publicis Groupe Global Creative Board. As a member of this committee that includes six creative entrepreneurs and leaders from all over the world, Alexandre is the only member of Brazilian nationality on this board. His career spans over three decades. If his recent accomplishments are any indicator as to what his level of passion is for the field of advertising, then we should expect even more exciting and creative work from Alexandre. His agency, Neogama, won a Cannes Film Festival award in 2015 for a campaign created for the Mix Brasil Festival.

Related:  http://www.meioemensagem.com.br/home/comunicacao/2016/01/07/alexandre-gama-deixa-cargo-global-na-bbh.html


Wen By Chaz Will Leave People In Awe

Just when others out there thought that Chaz Dean could not top himself, he has gone out there and done it again. That is his style and always will be his style as long as he is in charge. He does not look at these sorts of things as challenges. He looks at them as a chance to really improve his QVC advertised products, himself, and the way he goes about his business. He does not back down from it, not for a one second. In fact, it is just the opposite. He likes the chance to show people what he can do and what he is made out of as a businessman.

One of the smartest things about him is the fact that he keeps his ear to the ground and he truly keeps his pulse on the market. This allows him to have a firm grasp on what is popular, what is trending on Twitter, and what people are looking for in terms of hair-care products. With Wen By Chaz, it allows people to have their cake and eat it too, so to speak. It works as a styling treatment, shampoo, and conditioner. It does everything all-in-one. It is truly magic in a bottle.

The customers are over the moon about this because they are getting everything they could want and more out of a product with WEN by Chaz. The reviewers, oftentimes the hardest critics, are also extremely pleased with Wen by Chaz, as they have tried it out and seen the results for themselves, first-hand. Take, for example, this review by Emily McClure of Bustle.com: https://www.bustle.com/articles/136320-i-used-cleansing-cleansing-conditioner-on-my-fine-hair-heres-what-happened. She gave it high praise for what it did on her fine hair and the way it made her feel. It is very rare when a product can have that type of impact on a person’s confidence, but that is what Wen by Chaz does each and every day. Wen products are available on the Wen Website and the official Chaz Dean store (http://chazdean.com/store.aspx). Get yours today!


InnovaCare Health and Its Management

The main office of InnovaCare Health is located in Fort Lee, New Jersey. The firm provides services in the healthcare sector including physician services. The mission of InnovaCare Health is to bring revolution to the healthcare management and to eliminate the problems that people face in the current era of healthcare. The vision of InnovaCare Health is to foster a healthy relationship between the patient and the provider. The subsidiaries of InnovaCare Health support the organization. It comes up with healthcare plans that are affordable, coordinated, new, and quality driven. The patient comes first at InnovaCare. Their ultimate goal is to deliver quality medical care.

InnovaCare Health has been able to put a robust and efficient leadership team together. Dr. Rick Shinto heads the team. He is also known as Rick Shinto. Rick Shinto has more than 20 years of experience in the medical field. He serves as the current president and chief executive officer. Rick Shinto worked there as the CEO and President before Aveta Inc. was sold in 2012. Shinto was also part of the management team. He is in charge of the health plans of InnovaCare Health in Puerto Rico. Rick Shinto is a former employee of NAMM California. He was also the chief medical officer and the COO (chief operating officer) at Medical Pathways Management Company.

Rick Shinto moved to Cal Optima Health Plan, Orange County after working for one year at Medical Pathways Management Company. He worked as the company’s chief medical officer. Dr. Shinto is an author who writes on topics of clinical medicine and healthcare. He has a BS that he acquired from the University of California, a medical degree from the State University of New York, and an MBA that he got from the University of Redlands. The current chief administrative officer of InnovaCare Health is Penelope Kokkinides. She worked at the firm since 2015. Penelope has been working in the healthcare sector for approximately 20 years. She has lots of experience.

Read this article at openminds.com.

Penelope Kokkinides understands how to develop clinical programs and processes in managed health care. Penelope was the executive vice president at Centerlight HealthCare before joining InnovaCare Health. She also served at Touchstone Health as the chief operating officer. Penelope worked at AmeriChoice as the Corporate vice president of disease management and care management. She attended Binghamton University where she got her Bachelor’s degree in Biological Sciences and Classical Languages. Penelope also has a Master’s degree in Public Health. She acquired it from the school of Public Health at Columbia University.

Read more about Rick on Businesswire.

The Copa Star Takes The Hospital To The Next Level

In the medical industry, there are many aspects that comprise the total industry. Many people are not aware of all the various aspects that makeup the medical industry. However, most people are aware of several aspects that help to make the medical industry what it is today. One of the main aspects of the medical industry is the hospital. While it is one part, the hospital is a major part of the medical industry. It helps to bring all the various aspects of the medical industry together.

Medical professionals and patients come together in hospitals. Medical professionals come to provide medical care to the patients that come to hospitals. Almost all medical professionals assist with patient care at some point in their medical career at the hospital. As a core aspect of the medical field, the hospital serves numerous roles. One of the most obvious is medical care, However, there is much more to the hospital than medical care. The hospital is a business in its purest sense. One of the toughest parts of the hospital is taking the business and medical portions of the hospital and bringing the parts together.

Bringing the medical side and business side of the hospital together is tough. It takes professionals with the ability to handle all the various parts of the hospital. While there are medical professionals who handle the medical side of the hospital, there are also professionals who handle the business side. Hospital administrators handle the business side of the hospital, which involves pulling the medical side into the operations of the business side.

In recent years, many hospitals have seen that having hospital administrators with a business background is helpful in many ways regarding running hospitals. Business is a huge part of running hospitals, and hospital administrators with a business background bring a perspective that is unique in the hospital environment. A hospital in Brazil, which is named the Copa Star, has many people in the medical profession talking about the hospital. The hospital is considered a look into the future concerning hospitals.

The Hospital Copa Star is different than most hospitals. The Copa Star is more like a five star hotel concerning looks and business operations. The owners of the Copa Star wanted to build a hospital that provided a high level of medical service to its patients. However, the owners also wanted to provide a high level of customer service.

In addition, the owners wanted all patients and visitors to feel special while at the Copa Star. This is a main reason for the luxury hotel approach to the Copa Star. Business is at the root of the Copa Star, but medical care is at the core of what is done at the Copa Star. Read more at SSC Magazine about Hospital Copa Star.

Roberto Santiago’s Manaira Shopping Mall

Manaira Shopping Mall is one of Roberto Santiago’s ventures. It is the largest shopping center in Joao Pessoa. The entity has been seeking to ensure that customers have fun as they shop at the mall. The enterprise has continuously won the hearts of many customers who are great lovers of its rich cuisine, beautiful beaches and unique sunsets that lighten the northeastern city. Manaira shopping center offers a wide range of entertainment options, including movie theatres, electronic amusement park, bowling alleys and ballrooms among others. Manaira has 11 modern rooms, 3D rooms, and VIP rooms for cinema. The halls apply a stadium concept in the arrangement of seats to give a wider visibility to the customers. The mall has a complete bar that offers drinks, candy and gourmet popcorn.

The facility has pioneered in the idea of electronic amusement park, which is commonly known as the game station. The amusement park covers an area of 1,800 square meters and has over 200 machines for games and ballroom. It has a fully electronic space for contemporary audacious bowling lane. Manaira has many fitness centers and educational facilities like universities. Due to these numerous options for fun, leisure and entertainment, the shopping center has stood out among all other shopping malls in Paraiba. The facility has also strengthened its relationship with customers. In addition, the mall has other features, including a gourmet space for families. Here, people enjoy moments of tranquility and listen to music from the Domus Hall Concert on the rooftop of Manaira. Domus is one of the largest concert halls in Joao Pessoa. The modern and air-conditioned facility has advanced acoustic insulation and sound equipment. The concert hall hosts great national and international artists. The space is also available for graduations, private events, fairs, weddings, presentations and stand-ups. Read more on Polemica Paraiba.

About Roberto Santiago

Roberto Santiago is a Brazilian entrepreneur who also owns Mangeira Shopping Mall, one of the most contemporary shopping centers. He was born in Joao Pessoa. Roberto studied at Pio X Marist College before enrolling in the University Center of Joao Pessoa to pursue Business Administration. His career started at Café Santa Rosa before he established his cartonage company that specialized in manufacturing different utilitarian and decorative objects. Later, Roberto Santiago ventured into the allotment business. Since then, he has always achieved success in his endeavors. Roberto has a deep passion for sports. Over the years, he has won several trophies in kart championships and motocross. Read more articles on Roberto’s Blogspot

Securus Technologies Has A Great Customer Base

Securus Technologies is a great company, and one that is the leader in the public safety field. They have a great list of customers that use their technologies on a regular basis. One of them is the government, that uses them to ensure that their facilities are kept as safe as possible. They are pleased with the technologies and techniques that the company is creating.


One of the technologies that gives the facilities a lot to be happy about is Video Visitations. With the Video Visitations, inmates can now communicate with their loved ones easily. They can see and hear them, and it gives them a better overall attitude. The technology has led to much safer environments in the facilities, and their customers are very pleased with how it works for them.


The company invited their customers and the public to visit their facility in Dallas, TX for a presentation and a tour. This will allow them to see the latest technologies that they are working on, and why their inventions are so important to the safety of the public. Securus Technologies is known all over the world for their excellent work, and they are in high demand all across the country for what they can do. They have a staff that is dedicated and professional, and they are committed to providing excellent service. Since they are creating new technologies on a weekly basis, they will continue to lead the public safety field.

José Borghi is Brazil’s creative mastermind behind highly inventive commercials

The marketing genius, who’s success lies behind Mullen Lowe, Brazil’s incomparable and highly celebrated promotional groups, is Jose Borghi. One of Jose’s famous and endearing productions, is “Mammals Parmalat”. In this production, which was aired all over Brazil, children are singing and dancing to, Brazilian jingles, while dressed as if they are stuffed animals.

Jose’s victorious success, in the difficult vocation of marketing, started, when Jose was enrolled in middle school. His sister came to Jose one day, to interest him into going out with her, to view a presentation at the local theater. The theater was that showcasing a variety of highly creative videos, each of the videos, were famous, all over his homeland, for their clever presentation. The promotional videos that were presented that day at the theater, each conveyed well-known commercials, each of these videos, had earned for the creative minds behind their production, distinguished respect, from the esteemed Cannes Film Festival. Each of the creative producers of the commercials, was given an award. These stunning awards, resembling golden lions, captivated Jose. When he looked upon those attention-grabbing, lion awards, he knew immediately that he would work hard to become an original creator of commercials, too.

Jose attended the respected PUC-Campinas. It is there, that he earned his Advertising degree. Jose started his first job, in 1989, at the Standart Ogilvy. He added to his professional expertise, by working at Leo Burnett, and many others. It was not long, before Jose, with Erh Ray, established a promotional company, and founded the endeavor after their surnames, BorghiErh.

In time, they were purchased by Lowe. The name was then altered, to Borghi Lowe. The business venture prospered, achieving global recognition. Later merging, with Lowe & the Mullen Group, to found the enterprise, Mullen Lowe.

https://mullenloweopen.com/office/sao-paulo-2 for more.


Lori Senecal can increase your companies ability to thrive.

In a report by the Wall Street Journal, the renowned Lori Senecal is the hard working Global CEO of the celebrated agency, CP+B. Ms. Senecal is additionally, the former Global Exec Chairman, for the leading agency in its field, KBS. Lori is accountable, of steering the course of the proper outlook, to back MDC’s irreplaceable workflow. Ms. Senecal crusades sternly, in cooperation with MDC allied agencies, as a visionary coach, with the plan for commencing progress and unions. Ms. Senecal, is celebrated for aiding patrons to develop their routines by means of revealing competencies. Ms. Lori Senecal’s flair to take advantage of an agency’s overall methods and the ability to expand, was her chief interest, while employed by KBS.

Ms. Senecal produced the approach, for an unusual plan for invention and fashioned a fervor to go past creating overstatements, and ideally, takes advantage of established innovations. According to the Huffington Post, Ms. Senecal’s techniques are notable for hammering home KBS, as the agency, that people want. Ms. Senecal’s poise, supplies legitimate progress, to launch valid, satisfying challenges, for the company. While taking on her responsibilities at KBS, Ms. Senecal improved the agency, by educating on the implementation of existing tools, how to put together assets and develop supervision of content enhancements.

Lori strongly influences staff to manufacture their own occupational direction at the company. She has kept and also prompted, more than a few, plans that were predicted by staff, making use of motivational resistance, in connected agencies, with the objective of rousing staff and invigorating ingenuity. KBS grew from 250 employees, to 800 employees, under Ms. Senecal’s lead. The agency is ascribed as the principal agency to work for, in NYC. For a consecutive three years, the agency has been cited on the Ad Age’s fact list of Standout Companies, KBS has an wide reaching record of patrons, which include Victoria’s Secret, American Express, Harman and Vanguard, to list some, of prized, blue-chip agencies.

Prior to endeavoring at KBS, Ms. Senecal executed her duties as McCann Erickson’s President and the McCann Worldgroup’s respected Global Chief Innovation Executive.

Lori, the youngest of 3 children, attributes the majority of her strengths, to the order of her birth. Loris knows, that steady reminders, of her being younger than her siblings, compelled her to toil diligently, to transform into her own self made woman. Due to this, Ms. Senecal recognizes culture has a role on revolutionizing industry.